Sabtu, 09 Oktober 2010

[K379.Ebook] PDF Ebook Glial Physiology and PathophysiologyFrom Brand: Wiley-Blackwell

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Glial Physiology and PathophysiologyFrom Brand: Wiley-Blackwell

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells.

Coverae includes:

  • the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems
  • the cellular physiology of the different kinds of glial cells
  • the mechanisms of intra- and inter-cellular signalling in glial networks
  • the mechanisms of glial-neuronal communications
  • the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system
  • the cellular and molecular mechanisms of metabolic neuronal-glial interactions
  • the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's
Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it.
  • An up-to-date and fully referenced text on the most numerous cells in the human brain
  • Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system
  • Describes the role og glial cells in neuropathology
  • Focus boxes highlight key points and summarise important facts
  • Companion website with downloadable figures and slides

  • Sales Rank: #2352567 in Books
  • Brand: Brand: Wiley-Blackwell
  • Published on: 2013-04-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.70" h x 1.10" w x 6.70" l, 1.90 pounds
  • Binding: Paperback
  • 560 pages
Features
  • Used Book in Good Condition

Most helpful customer reviews

6 of 6 people found the following review helpful.
An Outstanding Book
By Philip Landfield
Although the importance of glial cells is often underappreciated, they are as critical as neurons in maintaining brain function. This outstanding book on glial cells provides a comprehensive treatment of their vast functions and attributes in a concise, entertaining and highly readable style. As such, this book will be a valuable resource for researchers and trainees at all levels, filling the large gap between current reference books and student textbooks. The authors are leading researchers of glial cell physiology and their expertise and insight allows them to present encyclopedic coverage of nearly all physiological mechanisms and functions of the major glial cell types. The book is thoroughly referenced and impeccably organized, covering physiological and pathophysiological functions of glia. An additional intellectually engrossing aspect of the book is that it describes the changing perceptions and roles of glial cells within the historical contexts of both the development of neuroscience and the evolution of the nervous system. The expertise of the authors also enables them to critically evaluate controversial issues, including the "...role of astroglial release of neurotransmitters", pointing out the pros and cons of current evidence and need for further research, perspective that will be beneficial to trainees and researchers in other fields. This book is essentially a must-have for all those interested in the basic biological functions of the brain.

1 of 1 people found the following review helpful.
Not to be missed !
By Maria Teresa Carri
As stated in the Preface, this book was written to fill the gap between an introduction to basic glia biology and a comprehensive reference book. The authors have perfectly centered the goal. Glial Physiology and Pathophysiology covers a number of aspects in this field, providing a most pleasant reading for students and researchers wishing to enlarge their view of neurobiology and understand the function and dys-function of neurons in the context of neighboring neuroglial cells.
The book begins with a captivating chapter on the history of discoveries in this field and develops to a detailed description of different types of glia and their function, physiology and contribution in neurological diseases.
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Not to be missed.

0 of 0 people found the following review helpful.
Excellent book
By Helen Wei
This is THE definitive introductory textbook on glial biology. It provides a comprehensive but digestible review of the glia field, and is a must-have for anyone studying neuroscience or interested in glial cells (particularly astrocytes) in the nervous system.

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Senin, 04 Oktober 2010

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  • Sales Rank: #3945301 in Books
  • Published on: 2011
  • Binding: Spiral-bound

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Jumat, 01 Oktober 2010

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Bright Dead Things examines the chaos that is life, the dangerous thrill of living in a world you know you have to leave one day, and the search to find something that is ultimately “disorderly, and marvelous, and ours.”

A book of bravado and introspection, of 21st century feminist swagger and harrowing terror and loss, this fourth collection considers how we build our identities out of place and human contact—tracing in intimate detail the various ways the speaker’s sense of self both shifts and perseveres as she moves from New York City to rural Kentucky, loses a dear parent, ages past the capriciousness of youth, and falls in love. Limón has often been a poet who wears her heart on her sleeve, but in these extraordinary poems that heart becomes a “huge beating genius machine” striving to embrace and understand the fullness of the present moment. “I am beautiful. I am full of love. I am dying,” the poet writes. Building on the legacies of forebears such as Frank O’Hara, Sharon Olds, and Mark Doty, Limón’s work is consistently generous and accessible—though every observed moment feels complexly thought, felt, and lived.

  • Sales Rank: #30842 in Books
  • Published on: 2015-09-15
  • Original language: English
  • Number of items: 1
  • Dimensions: .50" h x 5.40" w x 8.40" l, .0 pounds
  • Binding: Paperback
  • 128 pages

Review
Long list selection for the National Book Award for poetry
Best Poetry Book of 2015: New York Times and Buzzfeed

Praise for Bright Dead Things

"Effortlessly lyrical."—New York Times

"These poems are, as my students might say, hella intimate. They are meticulously honed and gorgeously crafted. They marry the lyric poem's interior emotional intensity with its exterior mode of social conveyance and aesthetic beauty. . . . The best compliment one can give a book of poems is that the book loves the reader. Bright Dead Things doesn't just love poetry; it loves the reader. My hunch is, Reader, you'll love it too.”—The Huffington Post

“Bright Dead Things, the fourth book of poems by Ada Limón, breeds a particular mixture of wildness. The mixture is by turns melodious and tight. Limón’s poems are like fires: charring the page, but leaving a smoke that remains past the close of the book.”—The Millions

"Limón’s work is destined to find a place with readers on the strength of her voice alone. Her intensity here is paradoxically set against the often slow burn of life in Kentucky, and the results will please readers."—Flavorwire

"Poet and Critic Stephen Burt says, 'Prose sense is to poetry as tonality is to music.' And I see that sense of prose cushioned in each poem included in this leguminous compilation. The works wear complexity on their sleeves with reassuring accessibility on their faces; to say it more succinctly, there’s a tough grilling of the soul and champagnes served to the measure of each one?s taste.”—The Rumpus

“In Ada Limon’s Bright Dead Things, there’s a fierce jazz and sass (“this life is a fist / of fast wishes caught by nothing, / but the fishhook of tomorrow’s tug.”) and there’s sadness—a grappling with death and loss that forces the imagination to a deep response. The radio in her new, rural home warns “stay safe and seek shelter” and yet the heart seeks love, risk, and strangeness—and finds it everywhere.”—Gregory Orr

"Ada Limón doesn't write as if she needs us. She writes as if she wants us. Her words reveal, coax, pull, see us. In Bright Dead Things we read desire, ache, what human beings rarely have the heart or audacity to speak of alone—without the help of a poet with the most generous of eyes."—Nikky Finney

"Limón does far more than merely reflect the world: she continually transforms it, thereby revealing herself as an everyday symbolist and high level duende enabler. At the end of one poem she writes, “What the heart wants? The heart wants/ her horses back,” and suddenly even this most urban reader feels wild and free."—Matthew Zapruder

"Both soft and tender, enormous and resounding, her poetic gestures entrance and transfix."—Richard Blanco

Starred Review "In her newest volume of poems, Limón (Sharks in the Rivers) delves into the divided self—self separated by geography, by loss, by change, by circumstance. VERDICT Generous of heart, intricate and accessible, the poems in this book are wondrous and deeply moving."—Library Journal

"A poet whose verse exudes warmth and compassion, Limón is at the height of her creative powers, and Bright Dead Things is her most gorgeous book of poems."—Los Angeles Review of Books

"Richly written and felt."—Publishers Weekly

About the Author
Ada Limón is the author of four poetry collections. Her work has appeared in The New Yorker, The New York Times, American Poetry Review, Oxford American, and Guernica. She lives in Kentucky and California.

Most helpful customer reviews

19 of 20 people found the following review helpful.
as all good writing should be
By Daniel Klawitter
"There remains the mystery of how the pupil devours
so much bastard beauty."

This one line from the poem "The Rewilding" captures my own response to this marvelously rich collection of poems.

Traversing the country of the heart as well as the actual landscapes of Kentucky and New York (where the poet divides her time), we as readers are treated as fellow travelers...privileged to have Ada Limon as our generous guide to striking emotional landscapes, audacious metaphors, and heart-wise reflections of place and home and homelessness.

The poet manages to weave narrative with nature, humor with pathos, the contemporary with the timeless echo of transcendent desire........so much bastard beauty indeed. And how she does it all is blessed mystery, as all good writing should be.

Torn
By Ada Limon

Witness the wet dead snake,
its long hexagonal pattern weaved
around its body like a code for creation,
curled up cold on the newly tarred road.
Let us begin with the snake: the fact
of death, the poverty of place, of skin
and surface. See how the snake is cut
in two—its body divided from its brain.
Imagine now, how it moves still, both
sides, the tail dancing, the head dancing.
Believe it is the mother and the father.
Believe it is the mouth and the words.
Believe it is the sin and the sinner—
the tempting, the taking, the apple, the fall,
every one of us guilty, the story of us all.
But then return to the snake, pitiful dead
thing, forcefully denying the split of its being,
longing for life back as a whole, wanting
you to see it for what it is, something
that loves itself so much, it moves across
the boundaries of death, to touch itself
once more, to praise both divided sides
equally, as if it was easy.

7 of 7 people found the following review helpful.
"Art should be a gift." Ada Limon
By Alarie Tennille
I’m grateful to another reviewer who introduced me to Ada Limon’s work with a link to the first poem, “How to Triumph like a Girl.” Not surprisingly, that poem won a Pushcart Prize. It also sent me straight to Amazon to place a book order. I love everything about Limon’s poems, their strong feminism, their humor and humanity, and their accessibility. I especially love how she deals with difficult issues that face us all (death, hospice, love entanglements) yet manages to leave us feeling uplifted, part of something greater than ourselves. As she said in a Q&A, “Life is suffering. Art should be a gift.” (I hadn’t finished the book before I looked her up on You Tube and watched two readings.)

Most of Limon’s titles are simple and serviceable, but a few are so captivating I’d jump to their pages in an anthology, like these two: “I Remember the Carrots” displays her fierce determination that surfaces again and again in a proud, ta-da! attitude. Limon often writes in almost a stream of consciousness that feels natural yet is surprisingly compact, taking you on a short, zig-zag path to a strong, unexpected ending. “Oh, Please Let It Be Lightning,” begins with a car trip discussion: “…your mother said she wasn’t sure/if one of your ancestors died in childbirth/or was struck by lightning.” The title would have been the expected punch line, but she ends the poem with a much grander bang.

I’d be reading along, simply enjoying the flow and tone of her work when a metaphor or simile would stop me in wonder. Here are a few of my favorites:

“…As if this big
dangerous animal is also a part of me,
that somewhere inside the delicate
skin of my body, there pumps
an 8-pound female horse heart,
giant with power, heavy with blood.”
(“How to Triumph Like a Girl”)

“If you walk long enough, your crowded head clears,
like how all the cattle run off loudly as you approach.”
(“During the Impossible Age of Everyone”)

“Below the grave, a cold spring runs.
Clear, like a conscience.”
(“The Rewilding”)

Limon has joined my list of favorite poets.

3 of 3 people found the following review helpful.
Love this book of poems! Reading this Book for the Sixth Time-- It's that good!
By K. Russell
This book should have won the National Book Awards...it's that good. Accessible, but smart, edgy, and interesting. Ada is an amazingly talented poet who writes in a beautifully musical way while also being able to tell a good story. This is in my top poetry books this year! Highly Recommend!

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